David Paul von Hansemann: Contributions to Oncology: Context, Comments and Translations

Ön Kapak
Springer Science & Business Media, 15 Şub 2007 - 371 sayfa

In 1890, just a few years after the discovery of the chromosomes, David Paul Hansemann, a pathologist-in-training with the famous Rudolph Virchow in Berlin, produced a theory of the pathogenesis of cancer involving the key current concept: that the first change which occurs in cancer is an alteration of the hereditary material of a normal cell at the site where the cancerous process begins.

In the process of linking cancer to chromosomal material, Hansemann coined the terms "anaplasia" and "dedifferentiation". These terms have remained the basis of descriptive terms concerning the microscopical appearances of tumours ever since. Nevertheless, despite the popularity of his terminology, Hansemann's ideas were attacked vigorously by almost all proponents of rival theories of the nature of cancer. Partly due to these disputes during his life-time, and partly due to other factors, interest in von Hansemann's ideas diminished during the twentieth century and his works are rarely mentioned today.

This book presents translations of all the relevant German texts, and analyses the background and context of Hansemann's theories as well as the reasons why he was almost completely forgotten. It shows that some of Hansemann’s ideas may still be relevant to cancer research today, and that he deserves to be remembered in relation to cancer as Vordenker unter den führenden Denkern seiner Zeit - The foremost of the leading thinkers of his time.

 

İçindekiler

Chapter
3
Postgraduate career
9
Chapter
10
Chapter
12
Chapter
25
Altruismcellular altruismandbiologistic sociology
32
Chapter
41
Embryology
46
Chapter
159
Chapter
179
Altruism
219
Anaplasia
234
Hansemanns other articles and books on tumours and related topics
277
On cure and curability 1897g
283
Malignant growths and normal reproductive tissues 1904q
289
What do we know of the origin of malignant tumours? 1905l
295

Capacity for independent existence in normal pathological
53
Embryonaltheories of cancer
61
Further analysis of the oogenic model
78
Hauptplasmen and Nebenplasmen
85
Critics reviewers the forgetting of Hansemann and what might have
91
Hauser FarmerMoore andWalkerBashford
104
Notes to chapter 6
117
On pathological mitoses 1891a
145
Atlas of Malignant Tumours 1910k
303
Experimental chemotherapy of animals with tumours 1912c
304
Appendix
317
Appendix D
331
Literature cited
347
Index
363
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